Blog

Introductory articles on peptide concepts, documentation and research.

Peptides

Peptide research

How to distinguish a scientific hypothesis from an established application.

View topics 3

1. What are research peptides?
2. Peptide research versus medicines
3. Peptide research as a route to future therapies

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Peptides

Peptides versus proteins

What these terms share, and why size does not tell the whole story.

View topics 5

1. What are the differences?
2. Amino acids
3. Peptides
4. Polypeptides and proteins
5. Peptide versus protein: which term should you use?

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Peptides

Peptide synthesis

From a planned sequence to production and verification.

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1. What is peptide synthesis?
2. How are peptides synthesised?
3. Peptide synthesis processes
4. The value of synthetic peptides

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Peptides

Peptide storage

Preservation starts with the conditions specified for each material.

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1. Best practices for peptide storage
2. Preventing oxidation and moisture contamination
3. Storing peptides in solution
4. Containers for peptide storage
5. Peptide storage guidelines: general tips

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Peptides

Peptide solubility

Why different sequences may behave differently in solution.

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1. What determines peptide solubility?
2. Peptide solubility guidelines
3. Predicting peptide solubility characteristics
4. Dissolving a peptide in solution

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Peptides

Peptide purification

Separating the target material is one step; demonstrating the result is another.

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1. Peptide purification
2. Removing specific impurities
3. Purification strategies
4. Main purification processes
5. Affinity chromatography (AC)
6. Ion-exchange chromatography (IEX)
7. Hydrophobic-interaction chromatography (HIC)
8. Gel filtration (GF)
9. Reversed-phase chromatography (RPC)
10. Compliance with good manufacturing practices (GMP)

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Peptides

Peptide purity

Understand what an analytical percentage tells you and which questions remain.

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1. How is peptide purity achieved and verified?
2. HPLC and mass spectrometry
3. What peptide purity level is recommended?
4. High purity (>95%)
5. Intermediate purity (>85%)
6. Lower purity (>70%)

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Peptides

Peptide bonds

An introduction to the chemical connection between units in a chain.

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1. What is a peptide bond?
2. Formation of peptide bonds
3. Structure of the peptide bond
4. The polarity of the peptide bond

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Peptides

Introduction to peptides

Essential concepts to begin reading about the subject.

View topics 5

1. What is a peptide?
2. How are peptides formed?
3. Peptide terminology
4. Peptide classification
5. Important peptide terms

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Educational content. It does not replace professional guidance, provide use protocols or establish regulatory authorisation for products.